Just like a picture doesn’t convey your personality, thoughts and dreams, sequencing your DNA doesn’t tell the doctor the details of what may be ailing you. Or how to best treat it. To truly understand disease, we must know the intricate patterns of collaborative behaviour of genes, and how these patterns may differ between healthy and diseased cells as well as between patients. Joana Gonçalves creates algorithms to unravel time-series of gene expression data, creating such in-depth cel-fies. She uncovers so-called functional modules and the regulators controlling these. No proverbial cure for cancer yet, but there isn’t much more room anymore for disease to hide.
Read more about Joana’s algorithms to unravel cellular dynamics here.